Innate generation of thrombin and intracellular oxidants in airway epithelium by allergen Der p 1

STAT3 mutations hence requires functional analyses in conjunction with the clinical diagnosis. Prabha Chandrasekaran, PhD* Ofer Zimmerman, MD* Michelle Paulson, MD Elizabeth P. Sampaio, MD, PhD Alexandra F. Freeman, MD Kathryn J. Sowerwine, MD Darell Hurt, PhD Julio C. Alc antara-Montiel, MD, PhD Amy P. Hsu, BA Steven M. Holland, MD From the Immunopathogenesis Section, Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md; the Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, Md; the Bioinformatics and Computational Biosciences Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md; and the Department of Molecular Biomedicine, CINVESTAV-IPN, Mexico City, Mexico. E-mail: [email protected]. *These authors contributed equally to this work. Disclosure of potential conflict of interest: The authors declare that they have no relevant conflicts of interest.